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Dr. Micera Alessandra

Head of Research Unit
MICERA ALESSANDRA
Unità di ricerca: RU Research laboratory
  • Analisi di biomarcatori candidati per la diagnosi precoce e monitoraggio della terapia in alcune malattie oculari invalidanti.
  • La complessa rete tra cellule e mediatori durante la risposta innata/adattativa, l'infiammazione e il rimodellamento tissutale
  • Contributo del fattore di crescita nervosa (NGF) nelle malattie infiammatorie allergiche croniche associate al rimodellamento dei tessuti e alla fibrosi, con un particolare interesse per le malattie della superficie oculare.
  • Sviluppo di modelli in vivo/in vitro (1D/3D).
  • Supporto alla diagnostica oculare attraverso lo sviluppo di Procedure Operative Standardizzate e l'utilizzo di strumenti di laboratorio (protein microarrays, HPLC, analisi molecolari e citometria statica/dinamica).
  • Progettazione e sviluppo di strumenti/strategie alternative non invasive per il campionamento e l'analisi in loco della superficie oculare e del segmento posteriore (dai fluidi oculari ai tessuti bioptici).

Medical activity: Works at IRCCS G.B. Bietti Foundation  in the offices of Via Livenza, 3 and Via di Santo Stefano Rotondo 6, Rome

Scientific publication  : PubMed

linkedin: Alessandra Micera

E-mail:----

  • 2020 National Scientific Qualification for Second Level Professor in disciplinary scientific sector 06 / F2 Diseases of the Visual System, valid from 09/11/2020 to 09/11/2029.
  • 2019 Enrollment in progress III year School of Specialization in Clinical Pathology and Clinical Biochemistry at the Catholic University of the Sacred Heart, Faculty of Medicine and Surgery, A. Gemelli University Polyclinic Foundation, Rome.
  • 2019 Registration in the Order of Biologists (22/02/2019); Register – Section A Registration number: AA_08224
  • 2010 Qualification to the profession of Biologist, University of Tuscia (Viterbo)
  • 2007 PhD in Immunology and Pharmacology, at the Hebrew University of Jerusalem (Israel); competence in immunopharmacology
  • 1993 Degree in Biological Sciences, “Sapienza” University (Rome). Neurobiologist.

• 1987 Diploma in Chemical-Biological Laboratory Technician, Armando Diaz State Professional Institute (Rome)

2018- Recruitment with permanent contract (full time), with the qualification of “Assistant Manager” (IRCCS Fondazione G.B. Bietti, Rome)

2018- Professor of University Master II level, UCSC (Rome)

2017/18-  Professor of II level University Master, Catholic University of the Sacred Heart (UCSC; Rome)

2015- Head of the research laboratories of the IRCCS-Bietti Foundation. Research and development laboratory in the biochemical, molecular and cellular fields applied to ophthalmological sciences (iso9001: 2015), Via Santo Stefano Rotondo, 6 – Rome

 2015- Co-supervisor for degree thesis and PhD (Medicine / Ophthalmology and Bioengineering),UCBM (Rome)

2014- Head of Ocular Surface Unit, at UCBM

2007-2013 Head of Line4-Anterior Segment and Ocular Adnexa (Line 4) and Head of the Ocular Surface Unit and the Ophthalmology Lab (Line4 / UO1)

2009 / 2010-2010 / 2011 – Member of the Research Council, CIR-Integrated Research Center (UCBM)

2005-2006–  Head of Line4-Ocular Surface and of the Ophthalmology Laboratory.

2003-2004–  Research fellow (Campus Bio-Medico University; Prof. Stefano Bonini)

2000-2002 / 2007–  PhD student (The Hebrew University, Jerusalem, Israel; Prof. Francesca Levi-Schaffer)

1994-1995 – Visiting researcher (Lab. Molecular Biology, Medical Research Council, Cambridge, UK)

1993-1999-  Thesis / graduate student and research assistant (Institute of Neurobiology, CNR; Dr. L. Aloe and Prof. R. Levi-Montalcini)

2009 / 2010-2010 / 2011 Member of the Research Council, CIR-Integrated Research Center (UCBM)

2003-2004 Research fellow (Campus Bio-Medico University)

2000-2002 / 2007 PhD training (The Hebrew University, Jerusalem, Israel)

1994-1995 Visiting researcher (Lab. Molecular Biology, Medical Research Council, Cambridge, UK)

1993-1999 Research assistant (Institute of Neurobiology, CNR, Dr. L. Aloe and Prof. R. Levi-Montalcini)

Principal Investigator in funded projects:

 

  • 2019-Grant National Research Program in Antarctica – PNRA D.D. 1314 of 25/05/2018 PNRA18_00341 – F – Coordinator and Head of the operational unit of the IRCCS-Bietti; research project: Tear-film Evolution in Antarctic Region: biostrumental, biochemical and behavioral PLAYers.
  • 2015-Grant from the Lazio Region: Research project funding (LR13 / 2008). Coordinator of the project and Head of the operational unit of the IRCCS-Bietti; research project: Arrays of electric transduction biosensors on polymeric films for diagnostic kits and therapeutic monitoring of ophthalmic diseases (FILAS-RU-2014-1112).
  • 2005-Grant from the Ministry: Finalized research. Project coordinator and Head of operational unit (UO1) of IRCCS-Bietti, research project: Stem Cells and regenerative cell therapies. Ocular surface reconstruction of burn patients with cultured conjunctiva flaps. 2
  • 1995-Grant Italian Multiple Sclerosis Association. Project leader; Nitric oxide and NGF in the induction and remission phases of experimental encephalomyelitis, CNR Institute of Neurobiology, Rome.

 

Collaborator within the UO of funded projects:

 

  • 2008-Fondazione Roma 9/9/2008: “Nerve growth factor (NGF) as a main actor in the activation / recruitment of ocular surface stem cells: in vitro and in vivo studies.”

2007-PRIN prot. 2007AF3XH4_001): “Development of the Nerve Growth Factor (NGF) as a drug for the treatment of eye and central nervous system diseases.”

Reviewer ad hoc: (Molecular Vision, British Journal of Ophthalmology, European Journal of Ophthalmology, Clinical and Experimental Ophthalmology, Journal of Proteome Research, Journal of Interferon & Cytokine Research, Journal of Cellular and Molecular Medicine, PLOS One/Biology) and International Grants

Member of scientific advisory board of Journal of Intercultural Ethnopharmacology e Journal Novel Immunology (Eagle Pushing Group, EPG).

Guest Editor (BioMed Research International; Special Issue Editorial 2015, article ID126582; IF 2.7) e Lead Guest Editor (2015; Journal of Ophthalmology; IF 1.9)

2002:“Travel Grant Award” for research abroad, XX Congress of the European Academy of  Allergology and Clinical Immunology (EAACI), May 9-15,

2001, Berlin, Germany; 2001: the UCB travel Grant/International Fellowship;

2001:Rita Levi-Montalcini Award for research abroad;

1999: Award-Foundation University of the Third Age, May 28th, Teatro Lirico (Milan).

1997:  International Award “Steven Newburgh”, nominata da Rita Levi-Montalcini;

1994, Fellowship Accademia Nazionale dei Lincei;

1993, Fellowship “Lions’ Club”

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